April 14, 2010Open Access

MicroRNA Cluster 221-222 and Estrogen Receptor α Interactions in Breast Cancer

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Abstract

These findings suggest that the negative regulatory loop involving miR-221-222 and ERalpha may confer proliferative advantage and migratory activity to breast cancer cells and promote the transition from ER-positive to ER-negative tumors.

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Leva et al. (Wed,) studied this question.

synapsesocial.com/papers/69d960d194760e72e6a3c1f1 https://doi.org/https://doi.org/10.1093/jnci/djq102

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