Does the presence of a bicuspid aortic valve alter ascending aorta hemodynamics compared to a tricuspid valve?
Bicuspid aortic valves are associated with altered ascending aorta hemodynamics, specifically increased and asymmetric wall shear stress, which is influenced by the fusion pattern.
The results of this study demonstrate that bicuspid valves induced significantly altered ascending aorta hemodynamics compared with age- and size-matched controls with tricuspid valves. Specifically, the expression of increased and asymmetric WSS at the aorta wall was related to ascending aortic flow jet patterns, which were influenced by the BAV fusion pattern.
Barker et al. (Sun,) studied this question.