Are specific cardiovascular biomarkers differentially associated with incident HFrEF versus incident HFpEF?
Different biomarker profiles predict incident HFrEF versus HFpEF, highlighting distinct pathophysiological pathways and a need for novel predictive biomarkers specifically for HFpEF.
Biomarkers of renal dysfunction, endothelial dysfunction, and inflammation were associated with incident HFrEF. By contrast, only natriuretic peptides and UACR were associated with HFpEF. These findings highlight the need for future studies focused on identifying novel biomarkers of the risk of HFpEF.
Boer et al. (Thu,) studied this question.