Pulse nav.journalClub Tendências Explorar Pesquisadores

Download the App

Join discussions, follow papers, and never miss your next session.

Download on theApp Store

© Synapse Social LLC, 2026

Política de privacidade

Início Explorar nav.journalClub Tendências

⌘+K

Anticancer and Apoptotic Effect of Alogliptin on A549 Cancer Cell Line | Synapse

April 12, 2026Open Access

Anticancer and Apoptotic Effect of Alogliptin on A549 Cancer Cell Line

Key Points

The aim is to investigate the anticancer effects of alogliptin on A549 cancer cells.
Measured DPP-4 inhibition
Assessed apoptotic pathway activation
Evaluated oxidative stress levels
Analyzed biomarkers including BAX, caspase-3, and MDA
Alogliptin significantly induced cancer cell death
DPP-4 inhibition correlated with enhanced oxidative stress
Apoptotic markers BAX and caspase-3 showed increased expression

Abstract

ConclusionS: Alo has caused cancer cell death through a variety of mechanisms, such as DPP4 inhibition, apoptotic pathway activation, and oxidative stress enhancement based on DPP-4, BAX, caspase-3, and MDA measurements.

Like

Bookmark

Share

View Full Paper

Cite This Study

Abbas et al. (Fri,) studied this question.

synapsesocial.com/papers/69db36a04fe01fead37c49cc https://doi.org/https://doi.org/10.36740/wlek/217851

Like

Bookmark

Share

View Full Paper