Implementação da calculadora de sepse de início precoce em uma UTI neonatal de cuidados terciários

Key Points

• The aim was to reduce unnecessary antibiotic use in infants at risk for early-onset sepsis by implementing a calculator.
• Quality improvement study conducted in a neonatal intensive care unit (NICU)
• Infants were divided into pre- and post-EOS calculator groups based on gestational age
• Implemented an EOS calculator and reduced the rule-out sepsis time frame from 48 to 36 hours for those on antibiotics.
• Percentage of NICU admissions started on antibiotics decreased from 62% to 51% (P < .01)
• In the chorioamnionitis subgroup, antibiotic starts decreased by 50% (P < .01)
• Reduction in days of therapy per 1,000 NICU patients from 168 to 110 (P < .01)
• Fewer blood cultures drawn, from 84% to 67% (P < .01)
• NICU length of stay reduced by 1 day, saving between $916,000 and $1.84 million per 1,000 patients.