Does the CHA2DS2-VASc score perform better than CHADS2 for predicting thromboembolism, and how does HAS-BLED perform for bleeding risk in patients with atrial fibrillation?
The CHA2DS2-VASc and HAS-BLED scores are effective and practical tools for predicting thromboembolism and bleeding risks in patients with atrial fibrillation.
Several independent risk factors (prior ICH, myocardial infarction, vascular disease, and renal failure) predict ischaemic stroke and/or the composite thromboembolism endpoint in AF, but thyroid disease (or hyperthyroidism) was not an independent risk factor for stroke. There is a better performance for CHA(2)DS(2)-VASc over CHADS(2) schemes for the composite thromboembolism endpoint. While both tested bleeding risk schemes have similar predictive value, the HAS-BLED score has the advantage of simplicity.
Friberg et al. (Fri,) studied this question.