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D-dimer is currently ordered in children for suspected PE in the emergency care setting, mostly in teenagers. The observed lower limit 95% CIs of 89% and 54% for diagnostic sensitivity and the specificity, respectively, suggest if used in patients with low-clinical probability, a normal D-dimer can safely exclude PE in children.
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Kanis et al. (Wed,) studied this question.
synapsesocial.com/papers/69dbd293387cf70698688d99 — DOI: https://doi.org/10.1136/archdischild-2017-313315
Jessica Kanis
Indiana University Health
Cassandra L. Hall
MedStar Washington Hospital Center
Jonathan Pike
Bryan Health
Archives of Disease in Childhood
Indiana University – Purdue University Indianapolis
Indiana University School of Medicine
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