January 29, 2022Open Access

TRPV4 contributes to ER stress and inflammation: implications for Parkinson’s disease

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Abstract

These results suggest that TRPV4 mediates ER stress and inflammation pathways, contributing to the loss of dopamine (DA) neurons in the SN and movement deficits in PD mice. Moreover, this study provides a new perspective on molecular targets and gene therapies for the treatment of PD in the future.

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Cite this study

Liu et al. (Sat,) studied this question.

synapsesocial.com/papers/69dd66ff80eea7d3f699c824 — DOI: https://doi.org/10.1186/s12974-022-02382-5

Authors

Na Liu

Kunming University of Science and Technology

Liping Bai

Macau University of Science and Technology

Zhipeng Lu

Kunming University of Science and Technology

Journals

Journal of Neuroinflammation

SHILAP Revista de lepidopterología

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Institutions

Kunming University of Science and Technology

Kunming Medical University

First People's Hospital of Yunnan Province

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Building similarity graph...

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TRPV4 contributes to ER stress and inflammation: implications for Parkinson’s disease

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Cite this study

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion