August 21, 2012

Benefits and Harms of Statin Therapy for Persons With Chronic Kidney Disease

Key Points

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Abstract

Statins decrease mortality and cardiovascular events in persons with early stages of CKD, have little or no effect in persons receiving dialysis, and have uncertain effects in kidney transplant recipients.

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Cite This Study

Palmer et al. (Tue,) studied this question.

synapsesocial.com/papers/69de658ee02db3e29db0c293 https://doi.org/https://doi.org/10.7326/0003-4819-157-4-201208210-00007

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1A prospective clinical trial comparing the treatment of idiopathic membranous nephropathy and nephrotic syndrome with simvastatin and diet, versus diet alone.1996 · 54 citations
2HMGCoA reductase inhibitors lovastatin and simvastatin in the treatment of hypercholesterolemia after renal transplantation.1993 · 21 citations
3Effect of fluvastatin on proteinuria in patients with immunoglobulin A nephropathy2000 · 77 citations
4Low-dose simvastatin is safe in hyperlipidaemic renal transplant patients1993 · 27 citations
5Effects of Atorvastatin on Kidney Outcomes and Cardiovascular Disease in Patients With Diabetes: An Analysis From the Collaborative Atorvastatin Diabetes Study (CARDS)2009 · 254 citations

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