February 14, 2018Open Access
View Full PaperSerum potassium and adverse outcomes across the range of kidney function: a CKD Prognosis Consortium meta-analysis
Structured PICO
Are outpatient potassium levels above and below the normal range associated with adverse outcomes across different levels of kidney function?
P
Population
Patients in the CKD Prognosis Consortium with varying levels of kidney function (eGFR and albuminuria)
I
Intervention
Outpatient potassium levels above or below the normal range
C
Comparator
Normal range outpatient potassium levels
O
Outcome
Adverse outcomes
Both hypokalemia and hyperkalemia are associated with adverse outcomes regardless of baseline kidney function.
Abstract
Outpatient potassium levels both above and below the normal range are consistently associated with adverse outcomes, with similar risk relationships across eGFR and albuminuria.