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Fixed drug eruption: pathogenesis and diagnostic tests | Synapse

June 30, 2009

Fixed drug eruption: pathogenesis and diagnostic tests

Key Points

Key points are not available for this paper at this time.

Abstract

Intraepidermal CD8+T cells may represent double-edged swords of the skin immune system with protective and destructive capacity.

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Tetsuo Shiohara (Tue,) studied this question.

synapsesocial.com/papers/69df05c5b8d7e9456661407a https://doi.org/https://doi.org/10.1097/aci.0b013e32832cda4c

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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Topotecan‐induced cellulitis‐like fixed drug eruption2002 · 16 citations
2T cell receptor (TCR) repertoire and function of human epidermal T cells: restricted TCR Vα-Vβ genes are utilized by T cells residing in the lesional epidermis in fixed drug eruption1996 · 31 citations
3Chronic fixed drug eruption caused by acetaminophen.1988 · 24 citations
4Direct Evidence for Interferon-γ Production by Effector-Memory-Type Intraepidermal T Cells Residing at an Effector Site of Immunopathology in Fixed Drug Eruption2002 · 123 citations
5Successful Desensitization to Fixed Drug Eruption: The Presence of CD25+CD4+ T Cells in the Epidermis of Fixed Drug Eruption Lesions May Be Involved in the Induction of Desensitization2004 · 54 citations