August 1, 2003

Role of S100A8 and S100A9 in neutrophil recruitment in response to monosodium urate monohydrate crystals in the air‐pouch model of acute gouty arthritis

CRCarle RyckmanHôpital du Saint-Sacrement SMShaun R. McCollThe University of Adelaide KVKaren VandalInstitut Universitaire en Santé Mentale de Québec

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Abstract

S100A8 and S100A8/A9 are essential to neutrophil migration induced by MSU crystals. These results suggest that they might be involved in the pathogenesis of gout.

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