April 26, 2006

Nonsteroidal Antiinflammatory Drugs During Third Trimester and the Risk of Premature Closure of the Ductus Arteriosus: A Meta-Analysis

Does short-term use of NSAIDs in late pregnancy increase the risk of premature closure of the ductus arteriosus?

Population

Pregnant women in late pregnancy (third trimester)

Intervention

Short-term use of Nonsteroidal Antiinflammatory Drugs (NSAIDs)

Outcome

Premature closure of the ductus arteriosussafety

Short-term use of NSAIDs in the third trimester significantly increases the risk of premature ductal closure.

Short-term use of NSAIDs in late pregnancy is associated with a significant increase in the risk of premature ductal closure.

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Cite This Study

Koren et al. (Wed,) studied this question.

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