A Nationwide Assessment of Anticholestatic Therapy Uptake in Patients With Primary Biliary Cholangitis: Opportunities for Optimisation

Key Points

• Assess the dosing of UDCA in Dutch patients with primary biliary cholangitis and identify optimization opportunities.
• Nationwide assessment of therapy uptake
• Analysis of UDCA dosing patterns
• Comparison of dosing based on biochemical response and body weight
• UDCA was often insufficiently dosed in patients.
• Opportunities exist for optimizing treatment in patients with better biochemical responses.
• Patients with higher body weight may benefit from adjusted dosing.