Modular design of dual-targeted, enzyme-responsive peptide carriers for gene drug delivery

Key Points

• To develop peptide carriers that can deliver gene drugs like siRNA and mRNA effectively and responsively.
• Utilized modular design principles to create peptide carriers
• Targeted dual mechanisms for enhanced delivery
• Employed enzyme-responsive elements for controlled release
• Demonstrated improved gene delivery efficiency
• Achieved enhanced intracellular release of therapeutic agents
• Showed potential for overcoming previous delivery challenges