What question did this study set out to answer?

To investigate how urogenital infections influence the discontinuation rate of SGLT2i medications in patients with Type 2 diabetes.

April 16, 2026Diabetes Obesity and Metabolism0 citationsOpen Access

Discontinuation of SGLT2i After a Urogenital Infection: A Population‐Based Matched Cohort Study of Patients With Type 2 Diabetes

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CLChristine LjungbergAarhus University Hospital MNMette NørgaardAarhus University CVChristina Vandenbroucke-GraulsAarhus University Hospital

Key Points

To investigate how urogenital infections influence the discontinuation rate of SGLT2i medications in patients with Type 2 diabetes.
Conducted a matched cohort study using population-based data.
Included patients with Type 2 diabetes who initiated SGLT2i.
Analyzed the incidence of SGLT2i discontinuation following UTIs and GTIs.
Patients experiencing a UTI or GTI had higher rates of SGLT2i discontinuation.
The elevated frequency indicates a significant association between infections and treatment discontinuation.

Abstract

Patients with Type 2 diabetes who initiate SGLT2i and experience a UTI or GTI within the following year have an elevated frequency of subsequent SGLT2i discontinuation.

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Discontinuation of SGLT2i After a Urogenital Infection: A Population‐Based Matched Cohort Study of Patients With Type 2 Diabetes

Key Points

Abstract

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