Renal Hemodynamic Effect of Sodium-Glucose Cotransporter 2 Inhibition in Patients With Type 1 Diabetes Mellitus

Key Points

• To investigate the renal hemodynamic effects of sodium-glucose cotransporter 2 inhibition in individuals with type 1 diabetes mellitus.
• Randomized trial with patients diagnosed with type 1 diabetes
• Intervention involved sodium-glucose cotransporter 2 inhibitors
• Trial registration identifier NCT01392560.
• Sodium-glucose cotransporter 2 inhibition improved renal blood flow measurements.
• Significant changes in kidney function markers were observed post-treatment.