Is cSCC Recurrence After Clear Margins a Sentinel Sign for Undiagnosed Immunosuppression?

Key Points

• To explore whether recurrence of cutaneous squamous cell carcinoma after clear margins indicates undiagnosed immunosuppression.
• Analyzed cases of cSCC post-surgery with clear margins.
• Reviewed patient histories for immunosuppressive conditions.
• Assessed recurrence rates over a specified follow-up period.
• Identified a notable percentage of patients with recurrence.
• Found a correlation between recurrence and immunosuppressed status.
• Highlighted a need for further immunological evaluation in recurring cases.