ABSTRACT We have developed a visible‐light‐driven photocatalytic protocol for the efficient synthesis of 3‐hydroxyindolenines under mild reaction conditions. The transformation proceeds via a photocatalytic oxidative process mediated by chlorophyll, which functions as a sustainable, metal‐free, and environmentally benign photocatalyst. Upon irradiation with visible light, chlorophyll is photoexcited to its reactive excited state, enabling effective single‐electron transfer (SET) and/or energy‐transfer pathways that promote the oxidative functionalization of the indole framework. This reaction facilitates selective oxidation at the C3 position of indole substrates, leading to the formation of 3‐hydroxyindolenine derivatives.
CHOUDHARI et al. (Wed,) studied this question.