Long-term sacubitril/valsartan is well tolerated in dogs with heart failure and myxomatous mitral valve disease and suggests excellent survival benefits

Key Points

• The study aims to evaluate the dosing schedule and clinical tolerance of sacubitril/valsartan in dogs with heart failure.
• Evaluated the dosing schedule of sacubitril/valsartan in canine patients.
• Assessed clinical tolerance over a long-term period.
• Collected data to inform future studies.
• Demonstrated that sacubitril/valsartan is well tolerated in dogs.
• Indicated potential survival benefits in dogs with heart failure and myxomatous mitral valve disease.