What question did this study set out to answer?

This research aims to explore the potential correlation between maintenance therapy and outcomes in diffuse large B-cell lymphoma (DLBCL).

April 24, 2026Open Access

Real-world efficacy of Bruton tyrosine kinase inhibitor based maintenance therapy in diffuse large B-cell lymphoma: a multicenter retrospective cohort study with external historical control

Key Points

This research aims to explore the potential correlation between maintenance therapy and outcomes in diffuse large B-cell lymphoma (DLBCL).
Conducted a multicenter retrospective cohort study
Evaluated efficacy of BTKi maintenance therapy
Compared results with external historical control
Noted a trend toward improved outcomes in DLBCL with maintenance therapy
Suggests potential benefit from BTKi maintenance therapy, warranting further controlled studies

Abstract

While limited by the retrospective study, our analysis raises the hypothesis that MT may correlate with improved DLBCL outcomes. A similar trend suggesting potential benefit from BTKi maintenance was noted, meriting further investigation in controlled settings.

Real-world efficacy of Bruton tyrosine kinase inhibitor based maintenance therapy in diffuse large B-cell lymphoma: a multicenter retrospective cohort study with external historical control

Key Points

Abstract

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