Malnutrition (MNA-SF ≤ 11) was independently associated with higher one-year mortality (17% vs 7.2%, HR 1.97) in chronic heart failure outpatients aged 75 years and older.
Does worse nutritional status increase one-year mortality in elderly patients with chronic heart failure?
In elderly patients with chronic heart failure, malnutrition (MNA-SF ≤ 11) is common and independently predicts one-year mortality.
Absolute Event Rate: 0% vs 0%
Malnutrition is common in patients with heart failure (HF) but its prognostic impact in advanced age patients remains unsettled. We sought to prospectively assess the impact the Mini Nutritional Assessment-Short Form (MNA-SF), in elderly patients with chronic HF. We analyzed data from the FRAGIC study a multicentre prospective registry conducted across 16 cardiology departments in Spain that included HF outpatients aged ≥75 years. From 499 patients (mean age 81.4 ± 4.3 years, 192 38% women), 235 had MNA-SF ≤11 (47%). Compared with patients with normal nutritional status, these patients were older (82 ± 7 vs. 81 ± 7, p = 0.047), more frequently women (45% vs. 33%, p = 0.005), and frail (66% vs. 43%, p = 1000 pg/ml: 77% vs. 65%, p = 0.005). During a median follow-up of 371 days, 58 patients (11.6%) died. One-year mortality was higher in patients with worse nutritional status (39 17% vs. 19 7.2%, p = 0.001), which was independently associated with one-year mortality (hazard ratio 1.97, 95% confidence interval 1.09–3.55, p = 0.02). A MNA-SF score ≤ 11 is common in older patients with chronic HF and it is associated with higher mortality at one-year follow-up. La malnutrición es frecuente en los pacientes con insuficiencia cardíaca (IC), pero su impacto pronóstico en pacientes de edad avanzada sigue sin estar claramente establecido. Nuestro objetivo fue evaluar de forma prospectiva el impacto del Mini Nutritional Assessment–Short Form (MNA-SF) en pacientes ancianos con IC crónica. Análisis del estudio FRAGIC, registro prospectivo multicéntrico que incluyó pacientes ambulatorios con IC de ≥75 años en seguimiento en 16 servicios de Cardiología en España. Se incluyeron 499 pacientes, edad media 81,4 ± 4,3 años, 192 (38%) mujeres. 235 pacientes presentaban un peor estado nutricional MNA-SF ≤11 (47%). En comparación con los pacientes con estado nutricional normal, estos eran de mayor edad (82 ± 7 vs. 81 ± 7; p = 0,047), con mayor frecuencia mujeres (45% vs. 33%; p = 0,005) y frágiles (66% vs. 43%; p1000 pg/ml: 77% vs. 65%; p = 0,005). Tras una mediana de seguimiento de 371 días, 58 pacientes (11,6%) fallecieron. La mortalidad al año fue mayor en los pacientes con peor estado nutricional (39 17% vs 19 7,2%; p = 0,001), lo cual se asoció de forma independiente con la mortalidad al año (HR 1,97; intervalo de confianza del 95%: 1,09–3,55; p = 0,02). Una puntuación MNA-SF ≤11 es frecuente en pacientes mayores con IC crónica y se asocia de forma con mayor mortalidad al año de seguimiento.
Díez‐Villanueva et al. (Wed,) reported a other. Malnutrition (MNA-SF ≤ 11) was independently associated with higher one-year mortality (17% vs 7.2%, HR 1.97) in chronic heart failure outpatients aged 75 years and older.