Unmet targets: evaluating vancomycin use and predictive factors of target attainment in hemodialysis patients

Key Points

• To evaluate the rates of vancomycin target trough concentration attainment in hemodialysis patients and identify predictive factors.
• Evaluated vancomycin trough concentrations across treatment courses in hemodialysis centers.
• Identified patient characteristics such as residual diuresis and treatment duration.
• Focused on therapeutic drug monitoring (TDM) for particular patient groups.
• Found a 0% target trough concentration attainment rate across all treatment courses.
• Identified patients with residual diuresis and those treated for less than 7 days as potential beneficiaries of closer monitoring for vancomycin TDM.