What question did this study set out to answer?

The study aims to identify urinary trehalase and NGAL as noninvasive predictors of end-stage kidney disease in ANCA-associated vasculitis.

April 25, 2026Open Access

Urinary NGAL and trehalase predict end-stage kidney disease in ANCA-associated vasculitis: a prospective cohort study

Key Points

The study aims to identify urinary trehalase and NGAL as noninvasive predictors of end-stage kidney disease in ANCA-associated vasculitis.
Conducted a prospective cohort study
Measured urinary trehalase and NGAL levels
Analyzed their predictive value for ESKD in AAV patients.
Urinary trehalase and NGAL are strong predictors of ESKD in AAV.
Combination of both markers improves risk stratification for patients.
Supports clinical utility in guiding personalized treatment decisions.

Abstract

Urinary trehalase and NGAL are strong, noninvasive predictors of ESKD in AAV, and their combination enhances risk stratification, supporting potential clinical utility for personalized treatment decisions.

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Cite This Study

Qiu et al. (Thu,) studied this question.

synapsesocial.com/papers/69ec5ae988ba6daa22dac75d https://doi.org/https://doi.org/10.1080/0886022x.2026.2650258

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