Manipulation versus steroid injection in the treatment of Morton’s neuroma: a randomized control trial | Synapse
April 25, 2026
Manipulation versus steroid injection in the treatment of Morton’s neuroma: a randomized control trial
Key Points
This research aims to compare the effectiveness of manipulation and steroid injections in alleviating pain and improving functionality in patients with Morton's neuroma.
Randomized control trial design
Participants received either manipulation or steroid injection for Morton's neuroma treatment
Self-reported levels of pain, discomfort, and functionality were measured.
Manipulation resulted in significant improvements in pain levels compared to steroid injection
Patients reported enhanced functionality after manipulation treatment
Retention of benefits was clinically relevant for those treated with manipulation.
Abstract
Manipulation elicited significant and clinically relevant improvements and retention in self-reported levels of pain, discomfort and functionality for patients electing treatment for Morton's neuroma.