Plaque erosion accounts for 30% to 40% of acute coronary syndromes and may be effectively managed with antithrombotic therapy without stenting, avoiding the risks of mechanical intervention.
The advent of intravascular imaging like OCT allows for the in vivo diagnosis of plaque erosion, potentially shifting the management of ACS towards tailored strategies.
Pathology and in vivo imaging studies have identified superficial plaque erosion as a frequent and important mechanism underlying acute coronary syndromes (ACS). In contrast with plaque rupture, the pathophysiological mechanisms leading to plaque erosion remain poorly understood. The advent of intravascular imaging techniques, particularly optical coherence tomography, has aided understanding of this mode of ACS in vivo by complementing previous insights from pathology studies. Appreciation of the distinct biological and clinical mechanisms of plaque erosion points to the possibility of tailored management strategies for patients presenting with ACS.
Partida et al. (Sun,) conducted a review in Acute coronary syndromes. Plaque erosion accounts for 30% to 40% of acute coronary syndromes and may be effectively managed with antithrombotic therapy without stenting, avoiding the risks of mechanical intervention.