Sutab, a sodium sulfate oral tablet, was developed as an alternative to traditional colonoscopy preparation (prep) solutions, which usually involve the ingestion of about three liters of a polyethylene glycol (PEG) solution to clear the bowels. This traditional method can be unpleasant, leading to barriers for patients seeking colonoscopies due to the large volume of distasteful fluid and resulting diarrhea. Sutab consists of 24 sodium sulfate tablets; patients are instructed to take 12 tablets the night before the procedure with at least 16 ounces of water, followed by another 12 tablets 5-6 hours prior to the colonoscopy. Patients must also consume an additional 32 ounces of water for hydration during the prep. However, as Sutab is relatively new, ongoing research is needed. A few studies indicated potential side effects, including incidences of erosive gastritis and gastric ulcers in patients who used Sutab, raising concerns about its safety, particularly for populations with existing health issues. Here we present a case of a 53-year-old woman who used this method for colonoscopy prep and experienced complications, and aim to provide suggestions on how to mitigate these side effects.
Machchhar et al. (Fri,) studied this question.