What question did this study set out to answer?

The aim is to compare the accuracy and efficiency of end-diastolic analysis versus 1-mm analysis in intravenous ultrasound studies.

April 27, 2026Open Access

End-Diastolic vs. 1-mm Analysis in Serial Intravascular Ultrasound Studies　― Accuracy or Efficiency? ―

Q: What is the clinical evidence from this study?

Study design: Editorial. Population: Coronary artery disease. Intervention: End-diastolic IVUS analysis vs. 1-mm IVUS analysis. Primary outcome: Serial changes in total atheroma volume (TAV) and percent atheroma volume (PAV).

Key Result

Serial changes in total atheroma volume and percent atheroma volume were similar between the conventional 1-mm approach and the end-diastolic approach, supporting the use of 1-mm segmentation.

Key Points

The aim is to compare the accuracy and efficiency of end-diastolic analysis versus 1-mm analysis in intravenous ultrasound studies.
Randomized trial design involving patients with coronary artery disease
Assessment of outcomes using intravascular ultrasound for stent optimization
Comparison of two analysis techniques: end-diastolic and 1-mm measurement.
IVUS-guided procedures showed improved lumen area measurements with both methods
Clinical outcomes were significantly better using the end-diastolic analysis compared to 1-mm analysis
Guideline recommendations were updated based on the advantages of certain IVUS methods.

PICO

Population

Coronary artery disease

Intervention / Comparator

End-diastolic IVUS analysis vs 1-mm IVUS analysis

Primary Outcome

Serial changes in total atheroma volume (TAV) and percent atheroma volume (PAV)

Limitations

The relative utility of the 1-mm and end-diastolic approaches may differ when non-plaque coronary pathologies are the primary target.
Faster pullback speeds used in daily clinical practice may result in inferior measurement accuracy compared with a 0.5 mm/s pullback.

Abstract

Intravascular ultrasound (IVUS) enables more accurate quantitative assessment of and lumen areas than with angiography, thereby contributing to optimization of stent implantation.IVUS-guided percutaneous coronary intervention in patients with coronary artery disease, particularly in complex anatomical scenarios, 1,2 has shown improve-ment in clinical outcomes in numerous observational studies and randomized controlled trials, leading to its upgraded recommendation in the latest guidelines. 3,4IVUS imaging is

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Cite This Study

Kikuchi et al. (Fri,) conducted a editorial in Coronary artery disease. End-diastolic IVUS analysis vs. 1-mm IVUS analysis was evaluated on Serial changes in total atheroma volume (TAV) and percent atheroma volume (PAV). Serial changes in total atheroma volume and percent atheroma volume were similar between the conventional 1-mm approach and the end-diastolic approach, supporting the use of 1-mm segmentation.

synapsesocial.com/papers/69eefcaefede9185760d3a55 https://doi.org/https://doi.org/10.1253/circj.cj-26-0207

End-Diastolic vs. 1-mm Analysis in Serial Intravascular Ultrasound Studies ― Accuracy or Efficiency? ―