Multiple organ dysfunction syndrome (MODS) is the terminal critical state of various acute severe diseases, characterized by progressive and reversible dysfunction of multiple organs, leading to complete systemic homeostasis collapse. This paper applies the 9-Keel unified theory and the four-dimensional D(t) dynamic imbalance index to construct a quantitative theoretical model for MODS progression. Based on core vital signs including body temperature, blood pressure, heart rate, and arterial blood pH, the model adjusts weight coefficients to reflect the progressive systemic imbalance characteristics of MODS, and takes the 0.5℃ micro-temperature deviation as the universal early warning threshold. The D(t) index stratifies MODS into four stages: steady state, single organ dysfunction, multiple organ progressive dysfunction, and irreversible systemic collapse. This study is a pure theoretical analysis and does not involve clinical diagnosis, treatment, or medical guidance. It further verifies the ultimate universality of the D(t) model in terminal acute critical diseases, and completes the theoretical verification system of acute critical diseases in the 9-Keel series.
FOO SENG ANG (Wed,) studied this question.