Management of recurrent venous thromboembolism and DOAC failure is addressed through a proposed group consensus and algorithm based on available non-randomized evidence.
How should recurrent venous thromboembolism be managed in patients who fail direct oral anticoagulants?
Provides a consensus-based management algorithm for patients experiencing recurrent VTE despite DOAC therapy, addressing a significant clinical gap.
Direct oral anticoagulants (DOACs) are the standard first treatment for patients with venous thromboembolism. Unfortunately, some patients develop recurrent thromboembolism despite adherence to anticoagulation. This remains a significant clinical challenge with no randomized data to guide therapy. This review summarizes the available evidence for the management of recurrent venous thromboembolism (VTE) and DOAC failure, and we propose our group consensus and management algorithm.
Eatrides et al. (Wed,) conducted a review in Recurrent venous thromboembolism. Management algorithm for recurrent VTE was evaluated. Management of recurrent venous thromboembolism and DOAC failure is addressed through a proposed group consensus and algorithm based on available non-randomized evidence.
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