Parvimonas micra promotes carcinogenesis of colorectal cancer through phenyllactic acid‐induced DNA damage

Key Points

• This research aims to explore how Parvimonas micra contributes to colorectal cancer through DNA damage.
• Investigated the role of Parvimonas micra in carcinogenesis using mouse models.
• Assessed the impact of phenyllactic acid on DNA damage in relation to colorectal cancer.
• Explored the effects of an AHR inhibitor on reducing carcinogenesis in mice.
• Parvimonas micra promotes carcinogenesis in colorectal cancer through inducing DNA damage.
• Aryl hydrocarbon receptor (AHR) inhibitor showed therapeutic potential in reducing cancer progression in mice.