The interplay between the pyramidalization of carbonyl carbons and the n → π* interactions in biomolecules

Key Points

• This research examines the relationship between pyramidalization of carbonyl carbons and specific interactions in biomolecules.
• Analysis of carbonyl carbon pyramidalization
• Study of n→π* interactions
• Review of conformational pre-organization effects
• Identified a connection between carbonyl carbon pyramidalization and interaction specificity
• Highlighted the role of conformational pre-organization in enhancing interactions