evaluation using a SARS-CoV-2 Spike subunit antigen indicates that P123/QS-21 is associated with enhanced systemic and mucosal antibody responses while inducing functional neutralizing activity. Together, these findings support cooperative supramolecular integration as a biomaterials design principle to modulate membrane activity and nanoadjuvant performance, providing a scalable and tunable framework for the development of subunit vaccine platforms.
Márquez et al. (Thu,) studied this question.