This study explores the intricate relationship between drinking water quality, nutritional status, and metabolic health, emphasizing the often-overlooked role of water in dietary assessments. Given that water constitutes a significant proportion of the human body and plays a central role in metabolic processes, its quality directly influences nutrient intake, hydration status, and exposure to harmful contaminants. The paper proposes a multidisciplinary conceptual framework linking physicochemical and microbiological water parameters to metabolic outcomes through nutritional pathways. The study highlights that drinking water can act both as a source of essential micronutrients and as a vector for toxic elements and organic contaminants, which may disrupt metabolic functions such as insulin regulation, lipid metabolism, and energy balance. Furthermore, microbial contamination may alter gut microbiota, leading to metabolic disturbances. To address these interactions, the paper outlines methodological approaches integrating water quality indicators, dietary intake, hydration biomarkers, and metabolic health metrics. At the population level, disparities in water access and quality contribute to unequal metabolic health outcomes, particularly among vulnerable groups. The study also identifies significant data gaps and methodological challenges in linking water quality to nutritional and metabolic indicators. Ultimately, the proposed framework aims to support future research, inform public health policies, and promote integrated strategies for sustainable water management and improved metabolic health.
Kibbou et al. (Thu,) studied this question.