Design, synthesis, and anti-inflammatory evaluation of new isatin azo disperse dyes: computational studies, molecular docking, and printing performance on polyester fabrics

Key Points

• This research aims to design and synthesize new isatin azo disperse dyes with anti-inflammatory properties.
• Synthesized and characterized novel isatin azo dyes.
• Conducted DFT and molecular docking studies to assess protein interactions.
• Evaluated printing performance on polyester fabrics.
• 5b identified as the most potent candidate with strong protein interactions.
• Dyes demonstrated excellent textile properties alongside notable anti-inflammatory activity.