Mechanical isolation of stromal vascular fraction using a spiral-based device: cellular outcomes and point-of-care workflow considerations

Key Points

• This study aims to characterize the BMC Uniq® SVF device and evaluate cellular outcomes of mechanical isolation of stromal vascular fraction.
• Characterized the BMC Uniq® SVF device for mechanical isolation of stromal vascular fraction.
• Compared cellular parameters of mechanical isolation with enzymatic isolation as a reference.
• Considered workflow factors for real-world implementation of the isolation device.
• Mechanical isolation using the BMC Uniq® device demonstrated favorable cellular outcomes compared to reference methods.
• Significantly enhanced standardization and reproducibility in stromal vascular fraction isolation were achieved.
• Workflow-related factors were crucial for the effective implementation of the isolation technology.