copies/L (99.9999% efficiency) within 72 h in laboratory microcosms and wastewaters, significantly suppressing horizontal gene transfer. Mechanistically, oxidative phase transformation of nZVI enhances inner-sphere Fe-O-P bonding to the DNA phosphate backbone, concentrating ARGs at the interface and promoting fragmentation. Transcript and protein assays demonstrate that ARG fragments activate Toll-like receptor signaling, thereby triggering a 5.71-fold increase in DNase II exocytosis. These findings support a hybrid nano-bio remediation strategy that couples interfacial capture with endogenous nuclease action, providing a scalable route to control emerging genetic pollutants in aquatic systems.
Building similarity graph...
Analyzing shared references across papers
Loading...
Yuqi Lu
State Key Laboratory of Pollution Control and Resource Reuse
Qinqin Cao
State Key Laboratory of Pollution Control and Resource Reuse
Wenhua Dong
State Key Laboratory of Pollution Control and Resource Reuse
ACS Nano
Zhejiang University
State Key Laboratory of Pollution Control and Resource Reuse
Building similarity graph...
Analyzing shared references across papers
Loading...
Lu et al. (Wed,) studied this question.
synapsesocial.com/papers/69fd7fa1bfa21ec5bbf08238 — DOI: https://doi.org/10.1021/acsnano.5c18556