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January 1, 2004Cardiology

There was no major arrhythmic event or mortality after TCP in the pacing group, whereas two patients (4%) in the non-pacing group died of ventricular tachyarrhythmias.

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Why the study?

Does transvenous temporary cardiac pacing prevent mortality or cause major arrhythmic events in patients with accidental digoxin overdose and symptomatic bradycardia?

Population

70 patients with accidental digoxin overdose and symptomatic bradyarrhythmias.

Comparison

Transvenous temporary cardiac pacing for a mean… vs No transvenous temporary cardiac pacing.

Design

Cohort

Authors

JCJu‐Yi ChenPLPing‐Yen LiuJCJyh-Hong Chen

Discussion

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Overview

Supports TCP safety in digoxin overdose bradycardia; hypothesis-generating for mortality benefit and should not yet change practice.

Structured PICO

Does transvenous temporary cardiac pacing prevent mortality or cause major arrhythmic events in patients with accidental digoxin overdose and symptomatic bradycardia?

P
Population
70 patients (30 men; age 74 +/- 12 years) with accidental digoxin overdose (serum digoxin > 2.0 ng/ml combined with digoxin-related symptoms) and symptomatic bradyarrhythmias.
I
Intervention
Transvenous temporary cardiac pacing (TCP) for a mean duration of 5.8 +/- 2.9 days.
C
Comparator
No transvenous temporary cardiac pacing.
O
Outcome
Major arrhythmic events or mortality.safety

Transvenous temporary cardiac pacing is safe and not associated with fatal arrhythmias in patients with accidental digoxin overdose complicated by symptomatic bradycardia.

Cite This Study

Chen et al. (2004) studied this question.

synapsesocial.com/papers/6a0059e6f9353b931b774809https://doi.org/10.1159/000080483
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