June 14, 2017

Recommendations for Cancer Surveillance in Individuals with RASopathies and Other Rare Genetic Conditions with Increased Cancer Risk

Key Points

Key points are not available for this paper at this time.

Abstract

mutations are present, and in patients with CBL syndrome. Also, the high brain tumor risk in patients with L-2 hydroxyglutaric aciduria may warrant regular screening with brain MRIs. For most syndromes, surveillance may be needed for nonmalignant health problems.

Bookmark

Cite This Study

Villani et al. (Wed,) studied this question.

synapsesocial.com/papers/6a02e96759ea043e4c9e35b9 https://doi.org/https://doi.org/10.1158/1078-0432.ccr-17-0631

Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

1Tyrosinemia Type I2014 · 30 citations
2A gene encoding a putative FAD-dependent <scp>l</scp> -2-hydroxyglutarate dehydrogenase is mutated in <scp>l</scp> -2-hydroxyglutaric aciduria2004 · 194 citations
3Von Hippel–Lindau and Hereditary Pheochromocytoma/Paraganglioma Syndromes: Clinical Features, Genetics, and Surveillance Recommendations in Childhood2017 · 279 citations
4Testicular yolk sac tumour in a patient with Sotos syndrome1999 · 6 citations
5Is medial temporal injury responsible for pediatric postconcussion syndrome? A prospective controlled study with single-photon emission computerized tomography2005 · 40 citations

Bookmark