Characteristic pulmonary impedance with exercise detected abnormal pulsatile hemodynamics in PH-HFpEF, which was not evident in precapillary PH (P=0.53).
Observational
Does characteristic pulmonary impedance with exercise detect abnormal pulmonary vascular response and RV-PA uncoupling in PH-HFpEF?
Abnormal exercise pulsatile hemodynamics may be key to right ventricular failure in left-sided heart disease (PH-HFpEF).
p-value: p=.53
BACKGROUND: , could precisely detect abnormal cardiopulmonary function in PH-HFpEF. RESEARCH QUESTION: with exercise detect abnormal pulmonary vascular response and RV-PA uncoupling in PH-HFpEF? STUDY DESIGN AND METHODS: ] ratio, from RV pressure-volume loops). Analysis included disease-specific autoregressive correlation structure of order 1 (for repeated measures in time-series analysis). RESULTS: = 0.11; P = .53). INTERPRETATION: in PH-HFpEF, which was not evident in precapillary PH, suggesting that abnormal exercise pulsatile hemodynamics may be key to RV failure in left-sided heart disease.
Lechuga et al. (Wed,) conducted a observational in Pulmonary Hypertension Resulting From Heart Failure With Preserved Ejection Fraction. Characteristic Pulmonary Impedance With Exercise vs. Precapillary PH was evaluated on Abnormal pulmonary vascular response and RV-PA uncoupling (p=.53). Characteristic pulmonary impedance with exercise detected abnormal pulsatile hemodynamics in PH-HFpEF, which was not evident in precapillary PH (P=0.53).