An in vitro blinded study demonstrates the utility of the Normalized TdP Score System for predicting the proarrhythmic risk of drugs.
: ≤ 0, > 0 to < 0.65 and ≥ 0.65, respectively, for low, intermediate, and high risk. This blinded study supports utility of our Normalized TdP Score System in predicting drug-induced TdP risks in 33 drugs, including 28 used for characterization of other assays under the CiPA initiative. However, these results need to be replicated in other laboratories.
Liu et al. (Mon,) studied this question.