Whole-genome sequencing and annotation of probiotic Bacillus amyloliquefaciens COFCAUP1

Key Points

• This study aims to sequence and annotate the genome of Bacillus amyloliquefaciens COFCAU_P1 to evaluate its probiotic traits.
• Genome sequencing was performed using Illumina NovaSeq.
• Phylogenomic analyses were conducted to assess safety and functional capabilities.
• Annotation of genes associated with stress tolerance, nutrient utilization, and immunomodulation was completed.
• The genome of Bacillus amyloliquefaciens COFCAU_P1 is 4.09 Mb in size and encodes 4,351 genes.
• Functional evidence supports its roles in antimicrobial defense and nutrient utilization.
• Phylogenomic analyses confirm its safety for use in aquaculture systems.