Hybrid Suture- and Plug-Based Closure Versus Dual Suture Devices in Transfemoral Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-analysis | Synapse
May 16, 2026Open Access
Hybrid Suture- and Plug-Based Closure Versus Dual Suture Devices in Transfemoral Transcatheter Aortic Valve Replacement: A Systematic Review and Meta-analysis
Key Points
This research aims to compare hybrid suture- and plug-based closure techniques with dual suture devices in transfemoral transcatheter aortic valve replacement.
Conducted a systematic review and meta-analysis of relevant studies
Evaluated outcomes associated with hybrid and dual suture closure techniques
Included studies that provided quantitative data for comparison.
Hybrid closure methods showed a significant reduction in overall complications compared to dual suture devices, with a complication rate of 5% (95% CI 3-8%) vs. 10% (95% CI 7-13%), P=0.02.
Mortality rates were lower in patients using hybrid methods (2% vs. 4%, P=0.04).
Hospital stay was significantly shorter for hybrid closure patients, averaging 3 days compared to 5 days for dual suture devices.