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January 1, 1980Nucleic Acids Research365 citationsOpen Access

Codon frequencies in 119 individual genes confirm corsistent choices of degenerate bases according to genome type

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RGRichard GranthamUniversité Claude Bernard Lyon 1CGChristian GautierUniversité Claude Bernard Lyon 1MGManolo GouyUniversité Claude Bernard Lyon 1

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Abstract

The poor printing of our previous Figure 2 (1) is corrected. Codon usage in mRNA sequences just published is also given. A new correspondence analysis is done, based on simultaneous comparison in all mRNA of use of the 61 codons. This analysis reinforces our claim that most genes in a genome, or genome type, have the same coding strategy; that is, they show similar choices among synonymous codons, or among degenerate bases (2). Like analysis on frequency variation in the amino acids coded reveals an entirely different pattern.

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Cite This Study

Grantham et al. (1980) studied this question.

synapsesocial.com/papers/6a081e347de338f10b108132https://doi.org/10.1093/nar/8.9.1893
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