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June 1, 1980CirculationOpen Access

Intraaortic balloon counterpulsation with and without reperfusion for myocardial infarction shock.

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Why the study?

Does intraaortic balloon counterpulsation combined with coronary artery bypass grafting reduce mortality compared to counterpulsation alone in patients with cardiogenic shock secondary to acute myocardial infarction?

Population

40 patients with cardiogenic shock secondary to acute myocardial infarction.

Comparison

Intraaortic balloon counterpulsation and… vs Intraaortic balloon counterpulsation alone.

Design

Cohort

Follow-up

long-term

Key result

Early reperfusion with counterpulsation within 16 hours of symptom onset significantly reduced long-term mortality compared to counterpulsation alone (25.0% vs 71.4%, p<0.03).

Authors

MDMarcus A. DeWoodRNRobert N. NotskeGHGerald R. Hensley

Discussion

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Overview

Early IABP plus CABG was associated with lower long-term mortality in MI shock; leaves open need for randomized confirmation before practice change.

Study Design

Type

Cohort (n=40)

Structured PICO

Does intraaortic balloon counterpulsation combined with coronary artery bypass grafting reduce mortality compared to counterpulsation alone in patients with cardiogenic shock secondary to acute myocardial infarction?

P
Population
40 patients with cardiogenic shock secondary to acute myocardial infarction.
I
Intervention
Intraaortic balloon counterpulsation and coronary artery bypass grafting (reperfusion).
C
Comparator
Intraaortic balloon counterpulsation alone.
O
Outcome
In-hospital mortality and long-term mortality.hard clinical

Main Result

Absolute Event Rate: 42.1% vs 52.4%

Early reperfusion with CABG combined with IABP significantly improves long-term survival in patients with cardiogenic shock complicating acute MI compared to IABP alone.

Cite This Study

DeWood et al. (1980) conducted a cohort in cardiogenic shock secondary to acute myocardial infarction (n=40). Intraaortic balloon counterpulsation and coronary artery bypass grafting vs. Intraaortic balloon counterpulsation alone was evaluated on in-hospital mortality. Early reperfusion with counterpulsation within 16 hours of symptom onset significantly reduced long-term mortality compared to counterpulsation alone (25.0% vs 71.4%, p<0.03).

synapsesocial.com/papers/6a085be6107d9dc00710790chttps://doi.org/10.1161/01.cir.61.6.1105
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