In a cohort of 4088 patients, metabolic syndrome resolution after bariatric surgery was less likely in those with older age, higher BMI, male sex, or Hispanic/non-Hispanic black race/ethnicity.
Cohort (n=4,088)
What are the predictors of metabolic syndrome resolution after bariatric surgery in an ethnically diverse adult population?
Bariatric surgery may be most effective for resolving metabolic syndrome in younger, less obese patients who are early in the course of their cardiometabolic disease, with notable racial and ethnic disparities in resolution rates.
OBJECTIVE: To determine predictors of metabolic syndrome and its resolution in a large, ethnically diverse adult population undergoing bariatric surgery. BACKGROUND: There is still limited knowledge about the impact of bariatric surgery on chronic health conditions such as metabolic syndrome. METHODS: Adults having had a laparoscopic Roux-en-Y gastric bypass or a laparoscopic vertical sleeve gastrectomy between 2007 and 2009 (n = 4088) without revision during the study period of January 1, 2007 through December 31, 2011 were eligible for the study. Diagnosis and resolution of metabolic syndrome were determined using standard criteria with electronic medical records of laboratory, diagnosis, and pharmacy information. RESULTS: Patients were primarily women (82%), non-Hispanic black (17%) or Hispanic (32%), 45 ± 11 years old, and had a body mass index (BMI) of 47.10 ± 7.73 kg/m at the time of surgery. After multivariate adjustment, metabolic syndrome was less likely to resolve in patients if they had a laparoscopic vertical sleeve gastrectomy procedure and a higher BMI at surgery, were older, were male or were either Hispanic or non-Hispanic black. The effects of age, race/ethnicity, and BMI at the time of surgery remained after accounting for weight loss. CONCLUSIONS: On the basis of our findings, bariatric surgery may be most effective for younger, less obese patients who are early in the course of their cardiometabolic disease. Future research should investigate the factors that lead to lower rates of disease resolution after bariatric surgery for racial/ethnic minority groups.
Coleman et al. (Mon,) conducted a cohort in Metabolic syndrome (n=4,088). Bariatric surgery (laparoscopic Roux-en-Y gastric bypass or vertical sleeve gastrectomy) was evaluated on Resolution of metabolic syndrome. In a cohort of 4088 patients, metabolic syndrome resolution after bariatric surgery was less likely in those with older age, higher BMI, male sex, or Hispanic/non-Hispanic black race/ethnicity.