What question did this study set out to answer?

The study aims to optimize the extraction of mangiferin from Mangifera pajang and evaluate its antidiabetic effects.

May 20, 2026Open Access

Ultrasound-assisted extraction of mangiferin from Mangifera pajang Kosterm. fruit using choline chloride-based natural deep eutectic solvent: Optimisation and antidiabetic activity

MRMuhammad Daniel Eazzat Mohd RosdanUniversiti of Malaysia Sabah MAMohd Azrie AwangUniversiti of Malaysia Sabah MBMohammad Amil Zulhilmi BenjaminUniversiti of Malaysia Sabah

Key Points

The study aims to optimize the extraction of mangiferin from Mangifera pajang and evaluate its antidiabetic effects.
Utilized ultrasound-assisted extraction with choline chloride-based natural deep eutectic solvent
Analyzed the extracted mangiferin for antidiabetic properties
Optimized extraction conditions for maximum yield
Significant increase in mangiferin yield with optimized conditions
Demonstrated antidiabetic activity in relevant assays
Highlighted the potential health benefits of bambangan as a functional food ingredient

Abstract

The growing demand for sustainable bioresources has highlighted the importance of exploring underutilised plant species as alternative sources of health-promoting compounds. Mangifera pajang Kosterm. (bambangan), an endemic and underexploited fruit...

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