Presence of right heart failure in patients undergoing TAVI was associated with significantly higher in-hospital mortality compared to those without right heart failure (7.57% vs. 1.11%, p<0.01).
Observational (n=383,860)
Yes
Does the presence of right heart failure worsen in-hospital outcomes in patients undergoing TAVI?
Right heart failure is a significant risk factor for increased mortality, complications, and resource utilization in patients undergoing TAVI.
Absolute Event Rate: 7.57% vs 1.11%
p-value: p=<0.01
Background: There are limited data on the impact of right heart failure (RHF) on patients undergoing transcatheter aortic valve implantation (TAVI). We investigated the mortality, in-hospital complications, length of stay, and total hospitalization charges for TAVI admissions, with and without RHF. Methods: We analyzed the National Inpatient Sample data from 2018 to 2022. The International Classification of Diseases–Tenth Revision (ICD-10) codes were used to define the patient cohorts. Propensity score weighting was used to balance patient demographic, hospital-level, and comorbidity data. Results: From 2018 to 2022, there were 383, 860 TAVI admissions, among which 1915 (0. 50%) had the presence of RHF. Compared to patients without RHF, mortality was higher in patients with RHF (7. 57% vs. 1. 11%, p < 0. 01). Similarly, acute kidney injury (37. 10% vs. 8. 56%, p < 0. 01), respiratory failure (12. 79% vs. 1. 91%, p < 0. 01), and use of mechanical circulatory support (11. 48% vs. 0. 83%, p < 0. 01) was higher in the cohort with RHF. Median length of stay (7 days vs. 2 days, p < 0. 01) and hospitalization charges (257, 239 vs. 180, 501, p < 0. 01) were higher in patients with RHF. Conclusions: In conclusion, we report that RHF is associated with increased mortality risk, complications, and resource utilization in patients undergoing TAVI. Right ventricular function should be a part of the evaluation for TAVI, given significantly elevated risks associated with its presence.
Kansakar et al. (Mon,) conduziram um estudo observacional na Implantação de válvula aórtica transcateter (TAVI) (n=383.860). Insuficiência cardíaca direita (ICD) vs. Sem insuficiência cardíaca direita foi avaliada em Mortalidade (p=<0,01). A presença de insuficiência cardíaca direita em pacientes submetidos à TAVI estava associada a uma mortalidade hospitalar significativamente maior em comparação com aqueles sem insuficiência cardíaca direita (7,57% vs. 1,11%, p<0,01).
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