Real-time cardiac MRI had 95.4% qualitative agreement with conventional MRI for left ventricular wall dynamics, but quantitative measurements were significantly lower (WM mean bias 0.49 mm, P<0.001).
Observational (n=31)
Does real-time MRI acquisition sequence accurately assess left ventricular wall motion and thickening compared to conventional breath-hold gradient echo acquisition in volunteers and patients?
Real-time cardiac MRI is suitable for qualitative assessment of left ventricular wall dynamics but is currently insufficient for quantitative analysis compared to conventional breath-hold gradient echo acquisition.
p-value: p=< 0.001
A real-time magnetic resonance imaging (MRI) acquisition sequence was evaluated for the assessment of left ventricular wall motion (WM) and wall thickening (WT). Ten normal volunteers and 21 patients were studied. Short-axis cine images of the left ventricle (LV) were acquired with a fast gradient echo and an ultrafast segmented echo-planar imaging (EPI) sequence. Qualitative and quantitative analysis of WM and WT was performed on a segmental basis. Qualitative scores agreed between the two methods in 691 of 724 segments (95.4%) with good reproducibility. Quantitative measurements of WM and WT were significantly lower (P < 0.001) with the real-time method (WM: mean bias, 0.49 mm; WT: mean bias, 0.61 mm). The largest differences were observed in the anterior and lateral segments and in patients with dilated ventricles. The lower resolution of the real-time sequence and artifacts was probably responsible for these differences. In conclusion, real-time cardiac MRI can be used for qualitative assessment of wall dynamics but is presently insufficient for quantitative analysis.
Plein et al. (Tue,) conducted a observational in Left ventricular wall dynamics assessment (n=31). Real-time magnetic resonance imaging (ultrafast segmented EPI) vs. Conventional breath-hold fast gradient echo acquisition was evaluated on Qualitative and quantitative analysis of regional left ventricular wall motion and wall thickening (p=< 0.001). Real-time cardiac MRI had 95.4% qualitative agreement with conventional MRI for left ventricular wall dynamics, but quantitative measurements were significantly lower (WM mean bias 0.49 mm, P<0.001).