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In Drosophila melanogaster, activation of prophenoloxidase with 2-propanol was analyzed. Prophenoloxidases A1 and A3 were activated within 1 sec after addition of 2-propanol. Activation of prophenoloxidase with 2-propanol is considered to be a reversible conformational change of the prophenoloxidase protein. J. Exp. Zool. 282:28–31, 1998. © 1998 Wiley-Liss, Inc.
Nobuhiko Asada (Tue,) studied this question.